Antibody
Actin, pan (ACTN05/C4)
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Clonality: monoclonal
Host: Mouse
Isotype: IgG1κ
Source: Lab Vision Thermo Scientific
Cat# MS-1295
Reference:
Kim, 2009
Formulation: liquid, purified with or without BSA and azide, or biotin labelled with BSA and azide
Reactivity:
Reacts in: Dog, Rabbit, Chicken, Cow, Pig, Human, Mouse, Rat, Dictyostelium
<em>Dictyostelium discoideum,
Physarum polycephalum</em>
Immunogen/Epitope
immunogen = Chicken gizzard actin
Specificity
reacts with all six known vertebrate isoforms of actin (MW~42kDa). It also reacts with two cytoplasmic actins (β, γ) which are highly homologous to one another but which differ from the muscle actins at about 25 amino acid residues; highly recommended for monitoring total protein load on Western blots
References
Paper Citations
- Kim M, Suh J, Romano D, Truong MH, Mullin K, Hooli B, Norton D, Tesco G, Elliott K, Wagner SL, Moir RD, Becker KD, Tanzi RE. Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity. Hum Mol Genet. 2009 Oct 15;18(20):3987-96. PubMed.
Further Reading
No Available Further Reading
Comments / Questions
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