Antibody

Actin (C4)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1κ
Methods: ELISA, IC, IH, WB
Source: Chemicon and Upstate are Millipore
Cat# MAB1501
References:
Liu-Yesucevitz, 2010
Nelson, 2007
Formulation: liquid, ascites, azide
Reactivity:
Reacts in: Various vertebrate

Immunogen/Epitope

immunogen = purified chicken gizzard actin (epitope near aa. 50-70)

Specificity

recognizes all six isoforms of vertabrate actin; reacts with both globular (G) and fillimentous (F) forms of actin and does not interfere with actin polymerization to form filaments

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References

Paper Citations

  1. . Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue. PLoS One. 2010;5(10):e13250. PubMed.
  2. . Familial Alzheimer disease-linked mutations specifically disrupt Ca2+ leak function of presenilin 1. J Clin Invest. 2007 May;117(5):1230-9. Epub 2007 Apr 12 PubMed.

Further Reading

No Available Further Reading