Antibody

4-hydroxyalkenals and MDA

Tools

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Clonality: kit
Host: Unknown Host
Source: OXIS International, Inc.
Cat# 21012
LPO-586™
Reference:
Ohsawa, 2008
Formulation: Colorimetric assay; for tissue homogenates, or cell lysates
Reactivity:
Reacts in: Various species

Immunogen/Epitope

based on the reaction of a chromogenic reagent, N-methyl-2
phenylindole (R1), with MDA and 4-hydroxyalkenals

Specificity

The LPO-586 method is designed to assay either MDA alone (in hydrochloric acid ) or MDA in combination with 4-hydroxyalkenals (in methanesulfonic acid); minimum interference from other aldehydes

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References

Paper Citations

  1. Ohsawa I, Nishimaki K, Murakami Y, Suzuki Y, Ishikawa M, Ohta S. Age-dependent neurodegeneration accompanying memory loss in transgenic mice defective in mitochondrial aldehyde dehydrogenase 2 activity. J Neurosci. 2008 Jun 11;28(24):6239-49. PubMed.

Further Reading

No Available Further Reading