For FTD Drug Development, a Q&A With Regulators
Regulators and industry scientists, and other steering committee members from the FTSG submitted questions to the U.S. Food and Drug Administration...
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Regulators and industry scientists, and other steering committee members from the FTSG submitted questions to the U.S. Food and Drug Administration...
Having a few excess polyglutamine codons—but not a lot—in the gene ataxin-2 predisposes a person to ALS, and scientists are just starting to figure out how...
Nursemaid oligodendrocytes care for neuronal axons not only by wrapping them in insulating myelin, but also by feeding them lactate...
Beth Stevens, Children’s Hospital, Boston, was one of 96 scientists and engineers who received Presidential Early Career Award for Scientists and Engineers...
Researchers report that AD-associated decline slows with advancing age, while “normal” aging-associated decline picks up...
What can big data do for medicine?...
The crimes of soluble Aβ continue to grow...
Researchers have discovered a gene that adjusts the course of amyotrophic lateral sclerosis, a fatal and rapidly progressing neurodegenerative disease...
Limiting caloric intake by 20 to 30 percent has been found to extend longevity in every creature from yeast to mammals, but can it make humans live longer—and healthier?...
Circadian rhythms are off in AD, illustrated in part by "sundowning," in which patients get confused and agitated late in the day and into the night...
Researchers report that Aβ oligomers can activate metabolic stress pathways by blocking protein translation...
Researchers have engineered a ring-based template for coaxing a wide range of peptides into β-sheet structures...
A subset of DJ-1-null mice has emerged with age-dependent, unilateral loss of dopaminergic neurons in PD-affected brain areas, followed by mild motor symptoms...
Globally, people with dementia still face significant social stigma, leading to feelings of isolation and marginalization...
Microchimeras—cells from another individual, commonly a fetus—have been detected in many human organs, but never before in the brain...
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