Is Structural MRI Closing In on Preclinical AD Biomarker?
New research boosts support for the use of magnetic resonance imaging (MRI) to identify seniors at the cusp of cognitive decline...
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New research boosts support for the use of magnetic resonance imaging (MRI) to identify seniors at the cusp of cognitive decline...
This scientific meeting that drew some 150 researchers to San Francisco 15-17 April 2013 featured an unusually broad array of topics...
Hunting for rare mutations that cause dementia, researchers have spotted, but not yet snagged, some tantalizing candidates.
The May 26 Nature Neuroscience online debuts 25 new candidate genes for amyotrophic lateral sclerosis...
The spotlight seems to be shifting to a greater interest in tau as a therapeutic target...
An excess of sirtuin one-ups mutant huntingtin in mice, saving neurons and delaying Huntington’s disease...
Sirtuins have been heralded as keys to longevity, based largely on studies in yeast, flies, and worms. New data now call these findings into question...
Polyphenols, plant compounds found in abundance in red wine and green tea, fight Aβ aggregation...
Is α-T catenin the elusive LOAD gene on chromosome 10? Or is it one of several genes? Read about Steve Younkin et al.'s presentation at the 8th International Conference on Alzheimer’s Disease and Related Disorders in Stockholm...
A parkinsonism-associated ubiquitin ligase interacts with parkin to promote mitophagy.
Researchers are finally getting a grip on the long-suspected link between mitochondria and not only PD, but other neurodegenerative diseases as well...
Rare variants of AD share some common areas of brain atrophy, but are also unique by way of degeneration in specific functional networks that correspond with clinical symptoms.
Is anyone, parent or physician, brave enough to allow gene therapy in newborn babies? The answer may come sooner than we think...
In spinal muscular atrophy (SMA), researchers have known for some time that motor neurons die for lack of the SMN (survival motor neuron) protein...
Extending in-vitro evidence that insulin-degrading enzyme (IDE) may be involved in the clearance of the Aβ peptide, a report in the 12 March issue of PNAS finds that IDE knockout mice have higher cerebral accumulation of both Aβ and the AβP intracellular domain...
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