An antibody against ApoE helps clear plaques and improves cognition in AD model mice.
Conformations of misfolded tau survive injection from one mouse to the next, a property shared by prions.
Tau and amyloid PET tracers demonstrate potential to sharpen the diagnosis of Alzheimer’s disease and frontotemporal dementias.
A single dose of a commonly prescribed antidepressant suppresses Aβ production in the human central nervous system.
People with Alzheimer’s disease and other dementias may benefit from creative activities, but hard studies are still lacking.
Deep-brain stimulation of the nucleus basalis of Meynert appeared safe and tolerable for Alzheimer’s patients.
Death receptor role in Alzheimer's disease looks less likely than was originally thought following a high-profile paper in 2009.
Resveratrol consumption failed to correlate with heart disease, inflammation, cancer, or even mortality in a community-based study. Are its benefits overstated?
MetLife rewards research on secretases, toxic Aβ transmission.
New twist to fluorescence-based microscopy lets scientists see up-close how Aβ aggregates in living cells.
A candidate reference method for measuring Aβ42 in cerebrospinal fluid brings researchers closer to standardization.
In award-winning documentary, son traces his mother’s progression into Alzheimer’s disease.
Playing nursemaid, TGF-β helps new neurons in the brain survive, develop, and migrate.
New NIH policies will require researchers to study male and female biology.
A close-up of the protein mayhem within the synaptic bouton offers scientists an unprecedented glimpse of the activity inside.