Death receptor role in Alzheimer's disease looks less likely than was originally thought following a high-profile paper in 2009.
X-ray crystallography reveals secrets of the glutamate receptor.
While mice sleep, neurons sprout synapses to solidify fresh skills, according to a new study. The brain also keeps amyloid-β levels low while we snooze.
New research suggests that α-synuclein comes in multiple strains, one of which seeds aggregation of tau.
In neurodegenerative disease, tau is in the dendrites, and scientists are beginning to flesh out ways to block what it does there.
New research strengthens the idea that microglia do far more than scour the brain for emergencies.
Researchers have co-opted a molecular transport system to shuttle Aβ antibodies across the mouse blood-brain barrier. They predict the shuttle could smuggle a variety of drugs into the brain.
An amplification-based test picks up minute amounts of prion protein in the blood of asymptomatic carriers, but researchers wonder whether regulators will want to screen the population.
A new project to identify factors that allow some carriers of pathogenic mutations to escape their genetic destinies could be applicable to neurodegenerative diseases.
A transcription factor thought to mark stressed-out motor neurons activates genes that help them survive. It maintains muscle mass, but not strength.
New strategies may help find and retain participants for Alzheimer’s trials.
Researchers have detected elevated endogenous tau in the cerebrospinal fluid of Aβ mouse models.
A study suggests that genes involved in Aβ production and endocytosis mediate ApoE4’s role in Alzheimer’s disease.
Activating translation regulator eIF2alpha restores plasticity and memory in Alzheimer's models.
Advances in RNA sequencing are shedding light on gene regulation and helping scientists make sense of data from genome-wide association studies.