As heat shock protein and co-chaperone team up to shield tau from degradation, they create toxic oligomers.
Amyloid fibrils seeded by Alzheimer’s brain extracts indicate that Aβ forms specific strains in different individuals.
New research connects extracellular Aβ to intracellular kinases that mediate its toxicity.
A new study supports the idea that non-motor symptoms of Parkinson's disease may aid earlier diagnosis.
New imaging data suggests degeneration of the fornix could help identify seniors on the verge of cognitive decline.
Older people improved memory and attention after playing a challenging video game, supporting the idea that multitasking could have benefits for cognition.
FUS, a protein tied to neurodegeneration, normally mends DNA breaks, according to a paper in Nature Neuroscience.
A deletion in chromosome 22 points to new genetic risk factors for Parkinson's disease.
It's not just for neurodevelopment anymore. Death receptor 6—known for pruning axons—also trims unused connections in adulthood, hinting at a function in Alzheimer's.
Proposed preclinical stages for Alzheimer’s disease predict well who is most likely to progress to Alzheimer’s dementia.
A new RNA interference therapy for amyotrophic lateral sclerosis has some success in mice and monkeys.
In the first study of its kind, researchers found a surprisingly low incidence of Lewy body dementias in a U.S. population.