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Caspase's Role in Apoptosis Clarified

Two recent papers describe the processes involved in the final stages of apoptotic cell death. During apoptosis, enzymes known as caspases break down cellular proteins, causing severe morphological changes and cell shrinkage...

New Alzheimer's Journal

Scientists often complain that scientific journals take too long to review manuscripts, and that subscription prices are unaffordable. A new journal devoted to Alzheimer's disease research, Alzheimer's Reports...

New Parkinson’s Gene

A gene on the long arm of chromosome 6 has been linked to an inherited form of Parkinson’s disease, called autosomal recessive juvenile parkinsonism (AR-JP)...

Success with Artificial Chromosomes

(From Nature Biotechnology press release.) Each cell in our bodies contains 46 chromosomes. But one day far in the future, doctors may give us an extra miniature chromosome containing therapeutic genes to treat disease...

A Role for a Synuclein Protein

Synucleins are small cytoplasmic proteins that are found in synaptic terminals. They are present in senile plaques and Lewy bodies (features of Alzheimer's disease and familial Parkinson's disease)...

Cholinergic Switching

Acetylcholine has different effects on the excitability of different neuronal types, according to work by Xiang, et al, published in today's Science. The researchers examined two subtypes of interneurons in layer V of rat visual cortex...

More Clues to Diet and Aging

Maybe it is time to give up steak in order to live longer—at least if you are a fruit fly. According to a study published today in Science, a diet of sugar keeps flies in a metabolic "waiting mode," in which both reproduction and death rates are low...

Membrane Rafts Revealed

It has been theorized that cell membranes contain stable regions consisting of glycolipids and cholesterol. They are called detergent-insoluble glycolipid-enriched membrane domains (DIGs)...

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