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A Prion Associate Is Fingered

The abnormal prion protein, but not the normal prion protein, binds with high affinity to plasminogen, a plasma component that has been linked to neurotoxicity, according to a report in the current Nature...

Reining in Macrophages

Macrophage activity is thought to play a key role in Alzheimer's and some other neurodegenerative diseases, such as ALS, as well as in autoimmune disorders. The mechanisms that regulate macrophages could...

GFAP Mutation in Alexander's Disease

The cause of Alexander's disease, a very rare, inherited CNS disorder, has been traced to the gene for glial fibrillary acidic protein (GFAP), according to a report published in this month's Nature Genetics...

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