Boost APP Ubiquitination, Wnt Signaling to Stave Off AD?
The prevailing theory that Aβ peptides are a major culprit in Alzheimer’s disease offers no shortage of possible therapeutic approaches...
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The prevailing theory that Aβ peptides are a major culprit in Alzheimer’s disease offers no shortage of possible therapeutic approaches...
Brain connections weaken years before cognition in sporadic and familial Alzheimer’s.
Preliminary data from Parkinson’s Progression Markers Initiative suggests that cerebrospinal fluid biomarkers distinguish the most rapidly progressing form of Parkinson’s.
Clogging the brain with Aβ drives up oxidative stress and stunts cerebral blood flow...
In neuronal transmission, as in real estate, location is everything...
Glutamate receptors at the postsynaptic membrane play important roles in neural plasticity...
As Alzheimer's disease progresses into the advanced stage, physicians and families often grapple with how to adjust a patient's treatment regimen...
Rather than sequestering Aβ to prevent its clearance from the brain, ApoE may indirectly block the peptide’s path to breakdown...
A diet deficient in omega-3 fatty acids interferes with synaptic function...
Activating just the β isoform of the estrogen receptor (ERβ) is enough to improve learning and memory in mice...
Before cognition falters, Alzheimer’s disease wreaks havoc on synapses, the brain’s subcellular communication hubs.
A method for examining the detailed structures of the intact brain with light microscopy debuts...
A group of scientists proposes an ambitious project to map the activity of every neuron in the brain, and correlate the data with behavior and disease states...
Scientists have drafted a new set of diagnostic research criteria redefining AD as a condition that develops decades prior to obvious symptoms...
Imagine a remote control that manipulates specific neurons in a mouse's brain while it scurries about its cage getting on with normal rodent business...