Soluble APP, Glycosylated Fragments Correlate With AD
Having established the first 42 amino acids in Aβ as a valid biomarker for AD, researchers are now turning their attention to all the other fragments of APP in the CSF...
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Having established the first 42 amino acids in Aβ as a valid biomarker for AD, researchers are now turning their attention to all the other fragments of APP in the CSF...
Genetics may play a bigger role in Parkinson's disease than previously appreciated...
Just as jammed highways can shut down cities, disrupted intracellular trafficking along axons can trigger neuronal death and neurodegenerative disease...
This week, Nature takes a broad look at the status of Alzheimer’s disease with a sponsored supplement...
Move over, green and related fluorescent proteins...
The family of low-density lipoprotein (LDL) receptors has captured the interest of Alzheimer’s researchers...
For researchers keen to understand ALS and other motor neuron conditions, making just a few motor neurons over months hampers their studies...
Immune cells have been shown to play a role in clearing Aβ from the brain, but it's not clear exactly which subset of cells is responsible...
In the search for what makes Aβ turn rogue and start gumming up the brain, a paper in Neuron fingers a novel suspect...
The 2011 Albert Lasker Basic Medical Research Award went to two scientists who established the role of molecular chaperones in protein folding...
It’s not that Alzheimer’s disease patients make too much brain Aβ; they’re slow at purging it—but why?...
Peptoids have been tested as possible antimicrobials and cancer drugs, but had not yet made their foray into neurodegenerative disease therapy...
Researchers have created a mouse model that selectively and reversibly overexpresses a mutant form of human amyloid precursor protein (APP) in the olfactory epithelium...
As direct-to-consumer genetic testing becomes increasingly popular, many have worried over how people will react to information about their genetic risk for diseases...
ALS has joined the growing list of neurodegenerative diseases characterized by fluctuations in the amino acid N-acetylaspartate (NAA)—but with a twist...