Excited Neurons Release More Aberrant Tau
Stimulating mouse neurons makes them pump out, and take up, more aberrant tau, intensifying its aggregation and possibly facilitating pathological spread.
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Stimulating mouse neurons makes them pump out, and take up, more aberrant tau, intensifying its aggregation and possibly facilitating pathological spread.
Three research groups turn induced pluripotent stem cells into what look like microglia.
Loose in the cytoplasm, TDP-43 heads straight for the neuronal powerhouses, sapping their ability to make energy.
Researchers in Collaboration for Alzheimer’s Prevention frame principles for what kind of data and samples to share and when to share them.
The United Kingdom’s exit from the European Union will likely slash funding, impede collaborations, and slow the pace of science.
Vascular troubles preceded amyloid deposition and other disease markers in a new Alzheimer’s progression model based on ADNI data.
Thirty years of medical data point to a growing number of people with the movement disorder.
Seeking strength in numbers, families gathered to swap stories and to learn about an upcoming DIAN-TU therapy trial geared specifically to their particular form of early onset AD.
Microglia and macrophages lacking the receptor consumed less amyloid in vitro, even when stimulated by anti-Aβ antibodies.
Assessed in toto, thousands of gene alterations portend changes in cognition, brain structure, and amyloid deposition in people without dementia. A step on the way to a gene chip for AD?
Could similar immune dysfunction contribute to neurodegeneration in people who carry repeat expansions in one copy of the gene?
A bill approved by the U.S. House Committee on Appropriations would increase funding for Alzheimer’s by $350 million.
At Keystone, researchers report the discovery of ion channels that shed light on the machinations of the brain’s microglia.
Researchers are discovering that microglia not only respond dramatically to their environment, but they also can quickly lose their identity.
People who report a prior head injury have no more chance of getting Alzheimer’s than the rest of the population, but they may be at higher risk for Parkinson’s.
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