Simple survey touted as a potential functional outcome in prevention trials.
In mice, the presence of mutant human tau disrupts synaptic signaling and slows down neuronal firing.
The Journal of Neuroscience retracted a paper that claimed Aβ does not accumulate inside neurons, and temporarily banished its senior authors.
Researchers at a Keystone meeting proposed that quelling inflammation outside the brain could slow the progression of Alzheimer’s and other neurodegenerative diseases.
Whether cleaning up plaques in AD or mopping up debris in the wake of a stroke, microglia get by with a little help from TREM2.
Large consortium releases epigenome profiles of 111 different tissues. They are already yielding insight into the immune system’s role in Alzheimer’s disease.
Skin side effect under investigation.
Routine cognitive screening could help doctors spot people at risk of dementia. Two new tests could make screening more accessible.
A debate has sprung up in response to a Cell essay arguing that the baby was thrown out with the bathwater when a γ-secretase inhibitor failed in Phase 3.
Alzheimer's Research UK has funded institutes at three universities to turn academic ideas into drug candidates.
Two studies suggest that the anti-inflammatory interleukin-10 prevents efficient plaque clearance and worsens AD-like pathology in mice.
Hollywood has discovered the narrative power of neurodegenerative diseases.
At Keystone, scientists reported that TREM2 may promote the survival of cells surrounding plaques, but where these cells come from and what they do is still up for grabs.
Alzheimer’s Disease Research Summit 2015: Three Years In Alzheimer's Disease Research Summit 2015: Expanding the Horizon Research Summit 2015 Recommendations Released The National Institutes of Health hosted a meeting earlier this month as leaders in ...
At an NIH conference in Washington, D.C., experts from beyond Alzheimer’s research discussed ways to beef up data collection and patient participation.
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