Researchers are discovering that microglia not only respond dramatically to their environment, but they also can quickly lose their identity.
At Keystone, researchers report the discovery of ion channels that shed light on the machinations of the brain’s microglia.
A bill approved by the U.S. House Committee on Appropriations would increase funding for Alzheimer’s by $350 million.
Could similar immune dysfunction contribute to neurodegeneration in people who carry repeat expansions in one copy of the gene?
Assessed in toto, thousands of gene alterations portend changes in cognition, brain structure, and amyloid deposition in people without dementia. A step on the way to a gene chip for AD?
Microglia and macrophages lacking the receptor consumed less amyloid in vitro, even when stimulated by anti-Aβ antibodies.
Seeking strength in numbers, families gathered to swap stories and to learn about an upcoming DIAN-TU therapy trial geared specifically to their particular form of early onset AD.
Thirty years of medical data point to a growing number of people with the movement disorder.
Vascular troubles preceded amyloid deposition and other disease markers in a new Alzheimer’s progression model based on ADNI data.
The United Kingdom’s exit from the European Union will likely slash funding, impede collaborations, and slow the pace of science.
Researchers in Collaboration for Alzheimer’s Prevention frame principles for what kind of data and samples to share and when to share them.
Loose in the cytoplasm, TDP-43 heads straight for the neuronal powerhouses, sapping their ability to make energy.
Three research groups turn induced pluripotent stem cells into what look like microglia.
Stimulating mouse neurons makes them pump out, and take up, more aberrant tau, intensifying its aggregation and possibly facilitating pathological spread.
Keystone Meeting on Microglia/Neurodegeneration: Here’s the Buzz Induced Microglia Make Debut at Keystone Symposium The THIK and Thin of Microglial Surveillance When a Microglia Is No Longer a Microglia Unbiased Screen Fingers TREM2 Ligands That Promote ...