A parkinsonism-associated ubiquitin ligase interacts with parkin to promote mitophagy.
The route to early dementia starts in adolescence, with low cognitive function and alcohol intoxication as major predictors.
Studies reported at AAIC demonstrate that biomarkers help predict who will develop cognitive impairment and dementia.
AD but no Amyloidβ? Researchers at AAIC 2013 theorized on the pathology underlying this form of dementia.
Cerebrospinal Fluid Tau Climbs in Aβ Mouse Models Coverage Denial For Amyloid Scans Riles Alzheimer’s Community Pooled GWAS Reveals New Alzheimer’s Genes and Pathways Are Subtle Memory Concerns a Sign of Future Dementia? Clinical Trials Roundup: Four Hits ...
Motor and cortical neurons are particularly vulnerable to FUSopathy. A new paper suggests they fail because they depend strongly on FUS to regulate transcription.
Activating translation regulator eIF2alpha restores plasticity and memory in Alzheimer's models.
Hunting for rare mutations that cause dementia, researchers have spotted, but not yet snagged, some tantalizing candidates.
Tau ligands for PET scans were among the hot topics at the Alzheimer’s Association International Conference in Boston.