Mouse studies point to a new pathway that mediates motor neuron disease caused by mutations in superoxide dismutase 1.
New research suggests that α-synuclein comes in multiple strains, one of which seeds aggregation of tau.
Courts in Europe revoked a patent that laid claim to all passive immunotherapy for Alzheimer’s disease, clearing the way for others to freely pursue this strategy...
Researchers identify the Aβ-binding scavenger receptor CD36 as a key regulator of macrophage inflammasome responses...
Scientists have discovered yet another function for β-secretase (BACE1), the enzyme that kick-starts amyloidogenic processing of the amyloid-β precursor protein...
A newly discovered lipid modification on the amyloid precursor protein may mark it for amyloidogenic processing...
Magnetic resonance spectroscopy bolsters hypothesis that ALS results from too much glutamate and too little GABA
Growing evidence suggests that innate immune cells prevent or slow Alzheimer's disease by chewing up Aβ and promoting its clearance.
Using hormone therapy early in menopause neither helps nor harms cognition, researchers report.
Similar to Alzheimer's disease, PD dementia begins with subtle deficits in cognition that progress to symptoms recognizable as mild cognitive impairment.
By looking for structural DNA variations in Alzheimer’s families, researchers identified 18 new genes that may play a role in AD pathology.
In a series of eight reviews, titled "Focus on Neurotechniques," researchers describe how approaches such as optogenetics and stem cells are revolutionizing neuroscience.
Eating fewer saturated fats and simple sugars reduces harmful forms of Aβ in the cerebrospinal fluid, scientists report.
The experimental drug NitroMemantine protects synapses from Aβ oligomer toxicity in mice by blocking extrasynaptic NMDA receptors.