Regulatory and pharma scientists fielded pleas from families with autosomal-dominant Alzheimer’s disease just prior to the AAIC conference.
Bypass budget promises tide may be turning on an underfunded disease as families with autosomal-dominant Alzheimer’s discuss how to navigate their daily challenges.
A sense of shared purpose energized a day of exchange between families with autosomal-dominant AD and researchers engaged in the Dominantly Inherited Alzheimer Network.
Probing this this Alzheimer’s risk factor, scientists find a novel variant, but no consensus yet on how this cell surface receptor increases risk for disease.
Enzyme converts pro-drug to estradiol in the cortex and hippocampus.
Massive Mouse Study Bolsters Rationale for Combination Therapy TREM2 Tidbits at AAIC: Genetics, Clinical Data New Data on Autosomal-Dominant Alzheimer’s Point to Early Fissures in the Brain’s Microarchitecture Aducanumab, Solanezumab, Gantenerumab Data ...
Dose permutations point to synergistic effects on Aβ and amyloid plaques.
Preventing these peripheral phagocytes from creeping into the brain improves memory and ameliorates pathology in mouse models of Alzheimer’s.
Researchers have published RNA expression and processing data for the cerebellum and frontal cortex, and find that C9ORF72-based ALS and sporadic disease differ greatly.
Last year's ice bucket challenge for amyotrophic lateral sclerosis netted $220 million in donations for ALS charities, and the 2015 challenge is off to a strong start with $100,000 from Major League Baseball. Alzforum looks at how all that money is ...
Patients and charities hope people will want to cool off again this summer.
A year after social media campaign, what happened with the money?
A new mass spectrometry analysis provides the most thorough catalog yet of modifications to tau.
Findings suggest a severe blow to the head twists the protein's backbone, which may lead to neurofibrillary tangles.
Clever optical corrections reveal microglia and neurons through the intact mouse cranium.