Seeking strength in numbers, families gathered to swap stories and to learn about an upcoming DIAN-TU therapy trial geared specifically to their particular form of early onset AD.
Thirty years of medical data point to a growing number of people with the movement disorder.
Vascular troubles preceded amyloid deposition and other disease markers in a new Alzheimer’s progression model based on ADNI data.
The United Kingdom’s exit from the European Union will likely slash funding, impede collaborations, and slow the pace of science.
Researchers in Collaboration for Alzheimer’s Prevention frame principles for what kind of data and samples to share and when to share them.
Loose in the cytoplasm, TDP-43 heads straight for the neuronal powerhouses, sapping their ability to make energy.
Three research groups turn induced pluripotent stem cells into what look like microglia.
Stimulating mouse neurons makes them pump out, and take up, more aberrant tau, intensifying its aggregation and possibly facilitating pathological spread.
Keystone Meeting on Microglia/Neurodegeneration: Here’s the Buzz Induced Microglia Make Debut at Keystone Symposium The THIK and Thin of Microglial Surveillance When a Microglia Is No Longer a Microglia Unbiased Screen Fingers TREM2 Ligands That Promote ...
A dynamic joint meeting dispels some old tenets while charting new avenues for research, such as microglia from iPSCs.
The co-chaperone DnaJC5 teams up with Hsc70 to guide potentially toxic proteins out of neurons. Whether this facilitates transcellular propagation remains to be seen.
Beginning in July, a massive open online course will summarize research on how to maximize brain health.
The kinase triggers a death cascade in animal models featuring endoplasmic reticulum stress. Active in ALS patients, it warrants a look as a potential therapeutic target.
Not exosome, not proteasome, not autophagy: Could a new pathway dubbed MAPS facilitate the spread of amyloidogenic proteins?
Large longitudinal study links tiny hemorrhages in cerebral capillaries to lower cognitive test scores, higher risk of dementia.