A new approach identifies a set of synaptic genes that influence the strength of connections in large brain networks.
Neuron-derived vesicles floating in the blood carry protein signatures that flag lysosomal dysfunction. Could they detect preclinical Alzheimer’s disease?
Tiny mesh electronics fold up neatly into the needle of a syringe and can be injected into the brain. The devices record neurons, and may do more in the future.
Arizona State University and Banner Health are hiring 20 scientists and their teams for a joint research institute dedicated to neurodegenerative diseases.
Treatment with the UPF1 gene prevented forelimb paralysis in rats.
In rat brains, aggregates that look like ribbons seeded Lewy bodies, while fibrils caused neurodegeneration and motor problems.
A genetic polymorphism in the human prion protein that shielded cannibalistic tribe members from the disease kuru could help researchers understand the structural biology of Creutzfeldt-Jacob disease.
Microglia internalize pathogenic forms of tau more robustly when anti-tau antibodies adorn the protein.
Could filling these cavities with a small molecule be therapeutic?
Alzheimer’s experts gathered in Las Vegas to chart a path for combination trials on repurposed drugs.
Researchers tie oligomers with different structures to distinct temporal, spatial, and cognitive effects in living brains.
Proper form and function of the brain’s immune cells depend on a diverse mix of “good” bacteria in the mouse intestine.
Levels of a neuronal protein in blood correlated with rate of decline in two U.K. cohorts.
A new study reports that Aβ disturbs sleep patterns that help cement memories.
However, once a person has ALS, diabetes does not affect how long they survive.