A study suggests that genes involved in Aβ production and endocytosis mediate ApoE4’s role in Alzheimer’s disease.
Leaders protest recent decision to deny Medicare beneficiaries coverage of amyloid scans.
Researchers have detected elevated endogenous tau in the cerebrospinal fluid of Aβ mouse models.
Epilepsy’s ties with Alzheimer’s disease occur earlier than previously thought.
Rare variants of AD share some common areas of brain atrophy, but are also unique by way of degeneration in specific functional networks that correspond with clinical symptoms.
The FDA and EMA have endorsed a new tool for modeling AD clinical trials to select the best design, potentially speeding up drug discovery.
Mouse studies point to a new pathway that mediates motor neuron disease caused by mutations in superoxide dismutase 1.
New research suggests that α-synuclein comes in multiple strains, one of which seeds aggregation of tau.
Courts in Europe revoked a patent that laid claim to all passive immunotherapy for Alzheimer’s disease, clearing the way for others to freely pursue this strategy...
A newly discovered lipid modification on the amyloid precursor protein may mark it for amyloidogenic processing...
Scientists have discovered yet another function for β-secretase (BACE1), the enzyme that kick-starts amyloidogenic processing of the amyloid-β precursor protein...
Researchers identify the Aβ-binding scavenger receptor CD36 as a key regulator of macrophage inflammasome responses...
Using hormone therapy early in menopause neither helps nor harms cognition, researchers report.
Growing evidence suggests that innate immune cells prevent or slow Alzheimer's disease by chewing up Aβ and promoting its clearance.
Magnetic resonance spectroscopy bolsters hypothesis that ALS results from too much glutamate and too little GABA