FUS, a protein tied to neurodegeneration, normally mends DNA breaks, according to a paper in Nature Neuroscience.
A new study supports the idea that non-motor symptoms of Parkinson's disease may aid earlier diagnosis.
Amyloid fibrils seeded by Alzheimer’s brain extracts indicate that Aβ forms specific strains in different individuals.
Older people improved memory and attention after playing a challenging video game, supporting the idea that multitasking could have benefits for cognition.
New imaging data suggests degeneration of the fornix could help identify seniors on the verge of cognitive decline.
New research connects extracellular Aβ to intracellular kinases that mediate its toxicity.
As heat shock protein and co-chaperone team up to shield tau from degradation, they create toxic oligomers.
The insoluble proteome from Alzheimer’s brains points to RNA processing proteins as a novel component of aggregates.
Fueling (or rekindling) controversy over anti-aging benefits of sirtuins, researchers report that Sirt1 lengthens lifespan in mice.
Without the protein beclin 1, rapacious microglia choke on amyloid β.
Researchers nabbed rare variants in Alzheimer’s genes by sequencing DNA from people with very high or very low levels of cerebrospinal fluid biomarkers.
Preliminary data from Parkinson’s Progression Markers Initiative suggests that cerebrospinal fluid biomarkers distinguish the most rapidly progressing form of Parkinson’s.
Researchers say that analyzing long stretches of homozygosity in people of Caribbean Hispanic descent represents an approach to finding rare, recessive Alzheimer’s mutations.
In sporadic and familial Parkinson's, faulty parkin may damage dopamine neurons by letting a deadly protein linger.
A stem cell-derived structure mimics crucial features of human brain development and could aid studies in schizophrenia, autism, maybe neurodegeneration.