Can Cancer Therapy Be Neurodegenerative Wonder Drug?
A cancer drug newly proposed for neurodegenerative diseases seems to do it all...
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A cancer drug newly proposed for neurodegenerative diseases seems to do it all...
With variants that boost risk for both familial and sporadic Parkinson’s disease, the LRRK2 gene beckons as a prime target for therapy development...
The subject of crosstalk between the peripheral circulation and the central nervous system permeated conversation...
As magnetic resonance imaging (MRI) resolution improves and more animal models become available, scientists are stepping up their use of mouse MRI...
Pyroglutamate Aβ is a particularly toxic version of the peptide at the center of AD pathogenesis; in fact, some scientists claim it seeds the formation of plaques...
For decades, scientists have debated whether peripheral cells cross the blood-brain barrier and what signals egg them on...
A failure to dispose of underperforming mitochondria may underlie the complex degenerative disorder known as multisystem proteinopathy...
if Charlie Glabe is right, an exploding neuron does expel material that then triggers the formation of new, stable matter in its surroundings...
Tau, α-Synuclein Spread: Crazy Stuff—How Might It Work? Like Star Born of Supernova, Plaque Born of Exploded Neuron? Can Dousing PyroGlu-Aβ Treat Alzheimer’s Disease? Field Ramps Up "Mini" Mouse MRI LRRK Watchers’ Eyes Turn to Inflammation, Auto
Last summer's news that a mutation in the amyloid precursor protein protects carriers against Alzheimer's disease made a big splash...
Many researchers believe that neurodegeneration's takeover of one's brain might be driven by pathogenic, misfolded proteins spreading through interconnected neural networks...
Growing evidence suggests that neurons begin faltering decades before cognitive symptoms in AD, but identifying the molecular culprits at play has proven challenging...
Among global initiatives aimed at understanding how biomarkers elucidate the progression of Alzheimer’s disease, DESCRIPA appears to do much with little...
Researchers have tried to tie M1 and M2 status to pathology in neurodegenerative diseases, but leaders in neuroinflammation are beginning to question their usefulness...
In the first GWAS based on amyloid imaging, researchers have uncovered single nucleotide polymorphisms near the genes encoding butyrylcholinesterase (BChE) and ApoE...