Research Brief: New Mouse Line for Studying Upper Motor Neurons
In the study of ALS, lower motor neurons in the spine have received the lion's share of attention—but now there is a tool to focus on the role of upper motor neurons in the cortex...
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In the study of ALS, lower motor neurons in the spine have received the lion's share of attention—but now there is a tool to focus on the role of upper motor neurons in the cortex...
Researchers using genomewide screens have identified two new loci for sporadic amyotrophic lateral sclerosis genes in the Han Chinese population...
For decades scientists have sought a way to sneak large drugs across the blood-brain barrier...
Microglia have taken center stage in Alzheimer’s disease (AD) research recently...
Why are women at greater risk for Alzheimer's disease?...
Rather than sequestering Aβ to prevent its clearance from the brain, ApoE may indirectly block the peptide’s path to breakdown...
A new recipe for cooking up cholinergic neurons from stem cells may help researchers study what goes wrong with these cells in Alzheimer’s disease...
When leaky blood vessels damage the brain, the organ’s stem cell niche dispatches a specialist crew of astrocytes to stop the bleeding...
Mutations that cause frontotemporal dementia may also predispose carriers to Alzheimer’s dementia...
As DIAN’s Scope Widens, Funding Narrows Dominantly Inherited Alzheimer Network Pharma Consortium Meeting 2013
Public funding is becoming so scarce that the DIAN researchers are increasingly asking industry to help...
A newly developed active amyloid-β vaccine removes Aβ from mouse brains while reducing inflammation and improving cognition...
One of the top Parkinson’s disease risk genes, GBA1, appears to be an even bigger risk factor for the related synucleinopathy dementia with Lewy bodies...
Therapies for amyotrophic lateral sclerosis (ALS) have proven hard to develop, in part because of inadequate disease models...
Researchers showed new data on how a therapeutic Aβ antibody their company had licensed from the Swiss biotech Neurimmune was measuring up...