A DNA-based Aβ vaccine appears safe and produces a strong immune response in monkeys, suggesting it could work in people.
Knocking down tau expression in adult mice diminishes induced seizures.
Update on compounds in Phase 2 and 3 trials from the Alzheimer's Association International Conference
Neurons clear misfolded proteins at different speeds. Is this why some brain regions are more vulnerable to neurodegeneration than others?
Researchers at AAIC 2013 report that an individual’s subjective sense of worsening memory could be an important predictor of cognitive impairment and dementia.
The proportion of seniors with dementia in England appears to be on the decline, new research suggests.
A study suggests that genes involved in Aβ production and endocytosis mediate ApoE4’s role in Alzheimer’s disease.
At AAIC 2013, researchers present the latest genetic risk factors for Alzheimer's disease.
Leaders protest recent decision to deny Medicare beneficiaries coverage of amyloid scans.
Researchers have detected elevated endogenous tau in the cerebrospinal fluid of Aβ mouse models.
Rare variants of AD share some common areas of brain atrophy, but are also unique by way of degeneration in specific functional networks that correspond with clinical symptoms.
Epilepsy’s ties with Alzheimer’s disease occur earlier than previously thought.
The FDA and EMA have endorsed a new tool for modeling AD clinical trials to select the best design, potentially speeding up drug discovery.
Mouse studies point to a new pathway that mediates motor neuron disease caused by mutations in superoxide dismutase 1.
New research suggests that α-synuclein comes in multiple strains, one of which seeds aggregation of tau.