15 Feb 2010
Researchers tried to make sense of the different cells and chemokine signaling pathways that might make the difference between quietly clearing Aβ and setting off a pro-inflammatory cascade...
15 Feb 2010
There’s more to the brain than neurons; astrocytes and microglia play crucial roles in the development and maintenance of a healthy brain...
13 Feb 2010
Histone deacetylase (HDAC) enzymes have been getting a lot of attention as targets for boosting neuronal survival and function...
12 Feb 2010
The results of the first U.S. Phase 2 trial for Dimebon in Huntington disease are finally out in print...
12 Feb 2010
When judging the utility of cerebrospinal fluid biomarkers in Alzheimer disease, it may be less a question of if, but rather when and in whom...
12 Feb 2010
The protein aggregates that brew discord in several neurodegenerative diseases may have some troublemakers in common...
09 Feb 2010
Might amyloid plaques suck the life out of neurons by trapping metal ions required for synaptic transmission?...
09 Feb 2010
Neuronal stem cells are proving to function like capable paramedics, coming to the rescue of degenerating neurons in multiple animal models of disease...
05 Feb 2010
Mitochondria take the stage in three recent papers...
05 Feb 2010
There are times in the course of scientific enterprise when researchers must re-evaluate their hypotheses in the face of new, unexpected data...
04 Feb 2010
The new animal models for TDP-43 proteinopathies, a series of related neurodegenerative diseases, are coming out at a fast and furious rate...
03 Feb 2010
The cellular prion protein has received a lot of attention recently for its potential role in amyloid-β (Aβ) toxicity...
03 Feb 2010
Death and taxes are reputedly inevitable, though death and receptors may be more interesting to Alzforum readers...
01 Feb 2010
Bigger, smarter, and more amenable than mice to the imaging techniques that are rapidly becoming indispensable in AD research, rats could be a valuable model for studying AD...
01 Feb 2010
Gizem Donmez reported that SIRT1 might protect against AD by boosting ADAM10 (aka α-secretase) and promoting non-amyloidogenic processing of Aβ APP...