M1 Muscarinic Receptors—Muscling APP to a Better End?
Activation of muscarinic acetylcholine receptors is known to steer APP down the non-amyloidogenic, α-secretase pathway...
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Activation of muscarinic acetylcholine receptors is known to steer APP down the non-amyloidogenic, α-secretase pathway...
People worried about a family history of Alzheimer disease may want to consider which parent was affected...
A study last year concluded, astonishingly, that the brain’s resident phagocytes had no impact on growth or clearance of Aβ plaques in AD transgenic mice...
New standards for reporting clinical trials were simultaneously published this week...
Researchers recently pegged the reticulon Nogo-A as a protective factor in amyotrophic lateral sclerosis...
The Michael J. Fox Foundation announced this week that it is offering LRRK2 antibodies to the Parkinson disease research community for testing...
Two new animal models may help researchers clarify the link between diabetes and Alzheimer disease...
A report offers a mechanism for how loss of locus ceruleus neurons could contribute to AD pathogenesis...
TDP-43 clogs neurons in some cases of amyotrophic lateral sclerosis, frontotemporal dementia, and Alzheimer disease...
Contrary to earlier dogma, scientists now know that the human brain does make new neurons throughout life...
A new study reveals an intriguing link between two top suspects in schizophrenia, neuregulin-1 (NRG1) and disrupted in schizophrenia-1 (DISC1)...
Shhh! Is silence conducive to learning and memory?...
In an era of genetics research where huge cohorts seem to be the name of the game, two new papers highlight the power of small...
Don’t let the name fool you; there’s nothing minor about microRNAs...
Exactly how does using one’s brain defend against the dreaded loss of faculties?...