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Fluorobodies Make Antibodies Green with Envy

Antibodies have proven to be extremely versatile tools for detecting proteins both in vitro and in vivo, but they need to be coupled to an additional label, such as an enzyme, radioisotope, or fluorophore. Now enter the "fluorobody," a molecule that combines...

New Orleans: Symposium Probes Why Synapses Are Suffering

Are you sometimes tempted to view APP and presenilin merely as raw material and machine for Aβ production, respectively? If so, think again, because that narrow spotlight is opening up to a broader understanding of how these two proteins function and might contribute to Alzheimer’s...

Copper to the Rescue?

After years as a potential but peripheral suspect in the pathogenesis of Alzheimer's disease, copper (Cu) is lobbying for a new designation—potential therapy! Two studies in the November 17 PNAS Early Edition suggest that copper can...

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