Amyloid Pompoms Decorate Capillaries in APP23 Mice
A new study shows striking images of early amyloid deposits on blood vessels of young APP23 transgenic mice...
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A new study shows striking images of early amyloid deposits on blood vessels of young APP23 transgenic mice...
Activating just the β isoform of the estrogen receptor (ERβ) is enough to improve learning and memory in mice...
The drug lithium is usually prescribed to patients with bipolar disorder. But evidence is growing that it might help with some neurodegenerative diseases...
Autophagy is a process by which cells engulf and degrade their own damaged organelles and aggregated proteins...
The relatively recent realization that neurogenesis is alive and kicking in the adult hippocampus has scientists wondering if the phenomenon can be exploited...
A multinational team of researchers has uncovered a chromosomal deletion that is associated with mental retardation and seizures...
One question in Alzheimer disease research is when in life the disease process actually begins...
Transthyretin is one of a handful of proteins that, like amyloid-β, can adopt a β-sheet conformation and aggregate as amyloid...
It’s safe to assume that for most Alzheimer researchers, the concept of a “supermodel” does not involve long legs and a pretty face...
Elevations in tau levels, and/or changes in its cellular distribution, disrupt microtubule function and axonal transport...
Fundamental knowledge gaps in Alzheimer disease research include a clear grasp of the normal role of the amyloid precursor protein (APP), and the molecular basis for the increased risk for AD as people age...
Thanks to a new imaging technology, researchers discovered that amyloid plaques can literally show up overnight and grow to their full size in just a few days...
A new functional MRI (fMRI) study shows how two regions of the brain prominently affected in Alzheimer disease cooperate to form new memories...
That new neurons are born in the adult mammalian brain is by now a foregone conclusion...
The discovery of microRNAs (miRNAs) opened a door on a previously unsuspected world of genetic regulation...