Paper Alert: PS1 Mutations Jinx Microglia Support for Neurogenesis
Researchers report a new role for certain presenilin-1 mutations that cause early-onset familial Alzheimer disease (eFAD)...
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Researchers report a new role for certain presenilin-1 mutations that cause early-onset familial Alzheimer disease (eFAD)...
Amyloid-β (Aβ) peptides in cerebrospinal fluid are among the few established molecular signs of impending Alzheimer disease...
While the media focuses on the next potential billion-dollar pharmaceutical treatment of AD, other investigators have been quietly cooking up alternative approaches...
Two anti-amyloid approaches—PBT2 and IVIg—came out with Phase 2 data at ICAD...
At the International Conference for Alzheimer’s Disease, several investigators presented data on compounds in Phase 2...
The newest potential protective factor for Alzheimer’s might be wrapped around your ring finger...
The development of tau-based drugs for AD depends on a deeper understanding of how tau begins to run amok in the first place...
Two papers out this week focus on mitochondria in neurodegeneration in general and Alzheimer disease in particular...
Another preclinical study presented at the ICAD capitalized on tau’s microtubule-binding property...
The International Conference on Alzheimer’s Disease featured some noteworthy preclinical and basic science tau developments...
Comparing neuropsychological test results against age-adjusted norms is one way of determining whether an individual might be facing impending dementia...
Chicago: Studies Probe Diminishing Placebo Decline, Part 1 Chicago: Studies Probe Diminishing Placebo Decline, Part 2 Chicago: ICAD Offered Mix Bag of Setbacks and Hopeful News Chicago: Trial Design Bedevils Search for New AD Drugs, Part 1 Chicago: The Ph
At the International Conference for Alzheimer’s Disease, investigators reported results on a range of different clinical trials...
One way to get the lowdown on someone is to check out the person’s closest friends and colleagues...
In mammals, molecular chaperones may help stave off neurodegenerative disease by steering proteins away from abnormal, toxic conformations...