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Wingless Pathway Helps Tauopathy Take Off

The microtubule-associated protein tau is the major component of the intracellular neurofibrillary tangles (NFT) found in patients with various neurodegenerative disorders, including Alzheimer's and frontotemporal dementia. Scientists know that hyperphosphorylation of tau is at the root of its pathology, but...

What Makes Amyloid Sticky?

Amyloid plaques are one of the hallmarks of Alzheimer's disease and were first described almost one hundred years ago by Alois Alzheimer. Today, however, their formation is still something of a mystery...

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