Keystone: Partners in Crime—Do Aβ and Prion Protein Pummel Plasticity?
Finding Aβ oligomers bound to cellular prion (PrPc) was absolutely unexpected...
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Finding Aβ oligomers bound to cellular prion (PrPc) was absolutely unexpected...
Considering how nasty amyloid plaques can be to nearby neurons, it should come as no surprise that these clumps of brain Aβ also fluster astrocytes...
So many different Aβs to measure, so little time—and funds...
Everything ages, and everything dies, but the mechanisms behind these processes are anything but clear...
Cells have more than one way to get rid of tau, the tangled protein in the brains of people with Alzheimer disease...
From clothing to computer chips, U.S. products are increasingly being made and tested overseas. The trend also applies to big pharma drugs...
At the Keystone symposium on Wednesday, debate on the last plenary talk continued around the dinner table and well into the poster session...
Yesterday, Takeshi Iwatsubo and Michael Wolfe shared the stage as recipients of the 2009 MetLife Foundation Awards for Medical Research in Alzheimer’s Disease...
The hunt is on for genetic variants that increase risk of sporadic amyotrophic lateral sclerosis—but the searchers are coming back empty-handed...
Though it’s now widely accepted that amyloid-β oligomers are bad news for dendritic spines, most of the data supporting this contention comes from cell culture or tissue slice experiments...
There’s new support for the idea that antibodies that stabilize normal prion proteins offer hope of fighting Creutzfeldt-Jakob and other prion-based diseases...
Using functional MRI (fMRI), researchers have mapped in fine detail a small set of cortical hubs...
Infamous among AD researchers for delivering the final cut that unleashes Aβ from its parent protein in neurons, γ-secretase has less-proclaimed physiological functions, too...
More so in the lab than on water, successful fishing expeditions are prized rarities...
The battle against ALS lost a soldier Monday when Sean Forrester Scott died in his sleep from complications of the disease...