Mitochondrial Chromosome Disintegrates in ALS Motor Neurons
Researchers have found that motor neurons from people who had died of ALS are likely to have mitochondrial DNA deficiencies and deletions...
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Researchers have found that motor neurons from people who had died of ALS are likely to have mitochondrial DNA deficiencies and deletions...
Five major pharmaceutical firms are pooling data on 4,000 patients across 11 failed trials into a joint database...
Researchers provide a link between the β amyloid peptide (Aβ) and abnormal fibrin clot formation in cerebral blood vessels...
Three national research agencies issued a joint press release announcing the signing of a cooperation agreement...
In recent years, mounting evidence has pointed to soluble oligomers of Aβ, rather than amyloid fibrils, as the most toxic species in AD...
Deep-brain stimulation looks to become popular for a number of neurological and psychological disorders, even as some of the scientific evidence remains scattered and spotty...
Better known as executioners, caspases have life-giving functions, too...
Researchers have described a protocol using magnetic beads...
Low circulating testosterone in older men is linked to an increased risk for Alzheimer disease...
Though it has been decades since amyloid-β was implicated in the pathology of AD, it is still not exactly clear how the peptide is toxic...
In a sign that prevention trials are shifting from “should do” to “will do,” academic and industry groups are getting serious about prevention trials...
Two recent papers provide more information about how motor neuron disease progresses in rodents...
The blend of AD and PD features in dementia with Lewy bodies (DLB) make it one of the most challenging neurodegenerative disorders to study...
Clinicians have long puzzled over the heterogeneity of Alzheimer disease symptoms...
Like alchemists aiming to turn base metals into gold, scientists are striving to convert one cell type into another—with a little more success...