ALS-FTD Mouse Model Develops Motor Neuron Disease
Mice expressing a mutant version of human UBQLN2 develop TDP-43 pathology in their spinal cords, while losing motor neurons, muscle mass, and muscle innervation of with age.
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Mice expressing a mutant version of human UBQLN2 develop TDP-43 pathology in their spinal cords, while losing motor neurons, muscle mass, and muscle innervation of with age.