Hardening of the arteries correlated with greater amyloid deposition in a longitudinal study, strengthening ties between cardiovascular disease and Alzheimer’s.
When a calcium sensor disappears from dendritic spines, synapse loss soon follows in Alzheimer’s models, aging mice, and diseased human brains.
IMAGINE that: Amyloid deposition shrinks in both treatment and placebo groups, dealing a blow to the anti-aggregation drug PBT2.
Astrocytes kindle neuronal hyperexcitability in mouse models of Huntington’s.
An antioxidant thought to boost mitochondrial function came up short in a large multicenter trial for PD treatment.
PINK1 mutations cripple mitochondrial energy production, raising new questions about Parkinson’s disease.
Keystone presenters pulled out new tools to make connections between genetics and disease.
Keystone symposium highlights new strategies in the quest to find the biomarkers of Parkinson’s disease.
Keystone Symposium: Alzheimer's Disease- From Fundamental Insights to Light at the End of the Translational Tunnel / Parkinson’s Disease: Genetics, Mechanisms and Therapeutics
Combination Trial Debate Energizes Keystone Symposium Protecting Neurons by Ramping Up Waste Disposal? Prodromal Initiative to Identify Biomarkers for Parkinson’s Researchers Build on GWAS to Parse Genetic Players in AD and PD More than 200 researchers ...
A Keystone symposium underscores the role of lysosomal dysfunction and vesicle trafficking in neurodegenerative disease.
The 2014 Alzheimer’s Association report finds that women bear the brunt of AD, being more likely to develop the disease or care for someone with AD full time.
Combination therapies may work where single drugs fall short, but testing them in AD may prove challenging.
Network analysis may explain why people with semantic dementia keep making memories even as their hippocampi degenerate.
A new test claims to detect Aβ oligomers in cerebrospinal fluid by exploiting their tendency to seed aggregation.
Researchers have found protein traces of brain damage in the blood of hockey players who sustained a concussion. Could biomarkers help decide when athletes return to their sport?