Finally, Therapies Targeting Huntingtin Poised for Clinic
Twenty years after the identification of the mutant gene that causes Huntington’s disease, scientists are ready to take therapies that target it into human trials...
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Twenty years after the identification of the mutant gene that causes Huntington’s disease, scientists are ready to take therapies that target it into human trials...
As attention shifts toward free-floating Aβ oligomers as the prime molecular culprits in AD, there is still plenty of confusion over the role of fibrillar amyloid...
Researchers reported in 2012 that the cancer drug bexarotene swiftly cleared amyloid-β and restored memory in transgenic mouse models of Alzheimer's disease...
Results of a two-year clinical trial suggest that a mixture of B vitamins slows atrophy up to sevenfold in areas of the brain that are vulnerable to degeneration in AD...
Scientists report the first successful generation of human embryonic stem cells via somatic cell nuclear transfer...
Scientists report that reducing hypertension may ward off amyloid pathology in people who have the ε4 version of the ApoE gene...
Alzheimer's disease researchers expressed sadness this week at the sudden death of Larry Sparks...
Are fewer people getting Alzheimer’s disease now than they did 20 years ago?...
Anticipating future clinical trials for Huntington’s disease, researchers are seeking sensitive measures that will predict onset and track progression...
Two new papers this month shore up the connection between cell waste disposal and function of neurons...
Skin cancer, a common and typically curable malignancy, may carry a fringe benefit—protection from Alzheimer’s disease...
Today, the MetLife Foundation honored Yueming Li and Lennart Mucke with its 2013 Awards for Medical Research in Alzheimer’s Disease...
Therapeutic Approaches Target Deubiquitinase, Protein Turnover Paracrine Signal From BACE1-Clipped Neuregulin Rescues Myelin Could Longevity Factor, Epilepsy Med, Treat AD One Day? The small scientific workshop From Science to Therapeutics: The Best Way
At a San Francisco conference addressing Alzheimer’s and related disorders, the agenda featured a diverse mix of topics—occasionally even from the same lab...
Scientists report that endocytosis whisks α-secretase away from the cell membrane in a process that seems regulated by neuronal activity...