Research Brief: SOD1 in Sporadic ALS Suggests Common Pathway
Mutated superoxide dismutase 1 contorts itself into strange and unnatural shapes, leading to amyotrophic lateral sclerosis...
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Mutated superoxide dismutase 1 contorts itself into strange and unnatural shapes, leading to amyotrophic lateral sclerosis...
A $40 million multicenter biomarker study for Parkinson disease progression is off and running, with enrollment underway at 10 of 18 sites in the U.S. and Europe. In design and operation, the Parkinson's Progression Markers Initiative (PPMI) follow
PPMI was launched in July with hopes of identifying a biomarker, or set of markers, that tracks the natural course of Parkinson disease...
One of the great challenges with developing treatments for neurodegenerative disorders stems from the capricious nature of disease progression...
Hard on the heels of a recent debate about the value of preventive measures for Alzheimer disease (AD) come some new data on physical activity...
Is apoptosis is a core process early in ALS, or merely the swan song of cells that have lost the ability to do anything other than make a graceful exit...
Gene therapy is an important research strategy and carries hope of becoming a viable treatment in neurodegenerative disease...
Two Faces of Evil: Cancer and Neurodegeneration Ipsen Colloquium on Alzheimer's Disease
Cancer and neurodegenerative diseases—what do they have in common, apart from the distress they cause to sufferers and their families?...
Researchers report that PGC-1α manages multiple genes that mitochondria need for biogenesis, electron transport, and glucose metabolism...
Immune cells cannot easily cross the blood-brain barrier to enter the central nervous system, but when they do reach the brain to fight infection, they don’t let go...
A report published online October 3 in Nature Genetics adds to the evidence for functional variants in NMDA glutamate receptor genes...
Could it be that a γ-secretase mutation helped give rise to communism?
Readers who followed Tom Fagan’s <a href="/news/conference-coverage/copper-mountain-fractious-receptors-glia-and-ad-pathology">Keystone Symposium coverage</a> of how a particular form of neuroinflammation...
In the race to understand the genetics of amyotrophic lateral sclerosis (ALS), the lowly zebrafish just might swim off...