Therapeutic Takedown: Hsp90 Inhibitors Tackle Tau
A pair of recent papers show that inhibitors of the chaperone heat shock protein 90...
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A pair of recent papers show that inhibitors of the chaperone heat shock protein 90...
If an old dog can learn new tricks, is it because Fido uses new neurons in the process?...
Elan and Wyeth announced on 21 May that they are planning to initiate a U.S. phase 3 clinical trial of AAB-001...
Boston: Clinical Trial Results for Dimebon Unveiled Boston: Resting State MRI Shows Loss of Network Connectivity Early in AD American Academy of Neurology: 2007 Annual Meeting
In a randomized, double-blind, placebo-controlled study conducted in Russia,...
One reason to study how brain systems develop is...
NAP, an octapeptide derived from activity-dependent neuroprotective protein (ADNP), reduces...
The twin lesions of Alzheimer disease—amyloid plaques and tau tangles—are mentioned in the same breath but...
Results of a randomized, placebo-controlled clinical trial suggest that coenzyme Q10 (CoQ10)...
No eye-popping action scenes, no happy ending...
A new technique for detecting proteins modified by β-N-acetyl-D-glucosamine (i.e., O-GlcNAc glycosylation) reveals that...
Two papers this week feature inventive strategies for uncovering...
What makes prions adopt toxic, self-perpetuating conformations?...
A new neuron in the adult hippocampus is a bit of a gatecrasher. It must act like...
Amyloid-β (Aβ) precursor protein (APP) has something of a mixed reputation...