Compounds that bind RNA temper toxicity related to ALS and FTD.
Connections across neural networks break down as cognition declines in people with different forms of AD, suggesting the wiring problems may be a hallmark of disease progression.
Researchers are ramping up efforts to target tau for Alzheimer’s and other tauopathies.
Blocking the microglial receptor for pro-inflammatory prostaglandin D2 protects motor neurons from glial toxicity in ALS cell and mouse models.
In gritty and sometimes harrowing detail, activist Meryl Comer describes the reality of caring for a loved one with Alzheimer’s disease.
Not the RNA aggregates, but the repeat dipeptides made from expansions in the C9ORF72 gene are responsible for neurodegeneration, a study claims.
Neurons derived from an octogenarian donor thrived in rat spinal cord lesions, extending thousands of axons along the length of the cord, even into the cortex.