Variability still plagues CSF biomarker measurements, but automated systems offer hope of a diagnostic assay.
Scientists are coming to grips with how tau spreads, and what the consequences are for the brain.
The protein normally comes in long and short isoforms, which hang out in the cytoplasm and on the nuclear envelope, respectively.
Researchers report multiple benefits of aerobic exercise on brain function, including some hints it could slow tau pathology.
At the right intensity and treatment duration, aerobic exercise can sharpen thinking skills and improve brain function even in cognitively impaired people, say researchers.
Polythiophene compounds stabilized prions and prevented them from spreading through the brains of infected mice. Researchers predicted the compounds could work on Aβ and tau, too.
At AAIC, new data on three anti-Aβ antibodies reinforced a sense of hope that Aβ immunotherapy may yet work out. Challenges with each antibody notwithstanding, all four leading candidates, including crenezumab, are now in Phase 3.
TDP-43 spots and expunges "cryptic" exons, study says.
Tiny injuries to capillaries in white matter, and to cells in gray matter, have come to be the focus of new imaging measures being explored in early presymptomatic AD.
100 DIAN Family Members Gather for Their First International Meeting At DIAN Family Meeting, Funding News Caps Talk of Inadequate Services Families Challenge DIAN Scientists to Do Even More, Faster Throughout the five days of the 2015 Alzheimer's ...
Regulatory and pharma scientists fielded pleas from families with autosomal-dominant Alzheimer’s disease just prior to the AAIC conference.
Bypass budget promises tide may be turning on an underfunded disease as families with autosomal-dominant Alzheimer’s discuss how to navigate their daily challenges.
A sense of shared purpose energized a day of exchange between families with autosomal-dominant AD and researchers engaged in the Dominantly Inherited Alzheimer Network.
Probing this this Alzheimer’s risk factor, scientists find a novel variant, but no consensus yet on how this cell surface receptor increases risk for disease.
Enzyme converts pro-drug to estradiol in the cortex and hippocampus.
No filters selected