Plaque Microglia—Mobile But Limited
In the April 16 Journal of Neuroscience, researchers give a vivid account of the microglia/plaque relationship...
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In the April 16 Journal of Neuroscience, researchers give a vivid account of the microglia/plaque relationship...
Blood levels of the antioxidant molecule urate are associated with the risk of progression in patients with Parkinson disease, according to a new study...
A company recently announced that it will start marketing a blood test for Alzheimer disease within the year...
Aβ oligomers made in test tubes or found in conditioned cell-culture medium can put a damper on synaptic plasticity...
The connection between synaptic activity and Aβ production in vivo runs through the endocytic pathway...
At the Keystone conference, researchers presented new data to argue that pyroglutamate (pGlu) derivatives of Aβ may be critically important in the underlying pathology of AD...
For the brave patients who elected to have foreign fetal neurons implanted in their brain as an experimental treatment for Parkinson disease (PD), there must have been many agonizing thoughts...
Perhaps no topic is hotter in Alzheimer disease molecular research today than the synaptic effects of amyloid-β (Aβ) oligomers...
To borrow IT-speak, “repurposing” is an underused art in Alzheimer disease drug research...
Antibody therapies for AD have galvanized researchers and affected families and observers from academia, industry, and even the investment community...
Eight years ago, JoAnne McLaurin’s research suggested that a particular stereoisomer of a inositol sugar alcohol might make a respectable AD drug...
The cholinergic hypothesis of Alzheimer disease tends to elicit a yawn from scientists who reserve their excitement for anti-amyloid treatments...
At the Alzheimer’s disease Keystone Symposium, held 24-29 March in Keystone, Colorado, a spate of news on potential future treatments capped a week of presentations...
Enlisting the immune system to fight Alzheimer disease can take the form of immunization against Aβ, or other attempts to modulate the inflammatory response that plays a role in disease...
The birth of new neurons in the adult brain intimates a capacity for restoration even in the face of aging and neurodegeneration...
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