CTAD: Solanezumab Seen to Nudge AD Ever so Slightly Tau Inhibitor Fails Again—Subgroup Analysis Irks Clinicians at CTAD Much ‘Adu’ About a Little: Phase 1 Data Feeds the Buzz at CTAD Tau-PET in Down’s: Unique Patterns Among Alzheimer’s Types and Stages ...
Patients on solanezumab saw small improvements on multiple secondary endpoints.
Researchers at SfN 2016 reported that oligomeric and exosomal forms in plasma predict AD as early as a decade prior to symptoms.
Where does TREM2-dependent microglial activity fit into the staging diagram of Alzheimer’s disease?
Despite conflicting results in the past, a large new study analyzing multiple statins in different ethnic groups suggests a protective effect from this class of medication.
Starting next month, Bart de Strooper will head national institute focusing on mechanistic research and evidence-based care.
Researchers at SfN 2016 proposed dialing up the immune response in Alzheimer’s brains to enhance phagocytosis.
At SfN 2016, researchers debuted new mouse models that may better represent human disease.
Researchers at SfN 2016 touted the advantages of APP knock-ins, but noted they are less useful than overexpression models for studying behavior.
Astrocytes and Exosomes Implicated in Protein Propagation Knock-In Alzheimer’s Mice Catch on More Broadly in the Field Next-Generation Mouse Models: Tau Knock-ins and Human Chimeras Inflammation Helps Microglia Clear Amyloid from AD Brains Exosomes and ...
Cell lines can serve as sensors for strains found in different human tauopathies.
Researchers at SfN 2016 painted a more detailed picture of how misfolded proteins may proliferate, as one cell spreads these “hot potatoes” to the next.
Diminishing Alzheimer’s pathology in mice appears to be as easy as shining a light in their eyes. Could it work in people?
Less aquaporin-4 in astrocytes surrounding blood vessels suggests impaired clearance of Aβ in people with AD.
In a PD mouse model, microbes pump out short-chain fatty acids that worsen synuclein aggregation and motor problems. Intestinal flora from people appears to do the same.