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APP Function: A Report from Bar Harbor

In August 2005, a group of researchers from inside and outside the field of Alzheimer disease met in Bar Harbor, Maine, with foundation and NIH representatives for two days of presentations and discussion at the fifth annual workshop on Enabling Technologies for Alzheimer's Disease Research.

BBB/Brain Vasculature: A Report from Bar Harbor

After release, some Aβ is degraded locally, a second fraction leaves the brain through interstitial fluid drainage and along brain arterioles, while another fraction is actively transported by proteins, such as LRP and glycoprotein-P, across the blood-brain barrier (BBB) into systemic circulation.

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