Since the discovery of nucleotide repeats in the C9ORF72 gene, the hexanucleotides have presented a puzzle for scientists...
Tiny blood vessels in the mouse brain crisscross the cortex, passing from one neural column to the next, like multiple streets between interconnecting city blocks...
As potential AD drugs continue to post disappointing Phase 2/3 results, many in the field are considering upping the artillery by testing experimental drugs in combination.
After more than a decade in the works, the long-awaited fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) arrived last month to little fanfare.
The experimental drug NitroMemantine protects synapses from Aβ oligomer toxicity in mice by blocking extrasynaptic NMDA receptors.
Eating fewer saturated fats and simple sugars reduces harmful forms of Aβ in the cerebrospinal fluid, scientists report.
In a series of eight reviews, titled "Focus on Neurotechniques," researchers describe how approaches such as optogenetics and stem cells are revolutionizing neuroscience.
Using hormone therapy early in menopause neither helps nor harms cognition, researchers report.
Magnetic resonance spectroscopy bolsters hypothesis that ALS results from too much glutamate and too little GABA
Growing evidence suggests that innate immune cells prevent or slow Alzheimer's disease by chewing up Aβ and promoting its clearance.
Courts in Europe revoked a patent that laid claim to all passive immunotherapy for Alzheimer’s disease, clearing the way for others to freely pursue this strategy...
Researchers identify the Aβ-binding scavenger receptor CD36 as a key regulator of macrophage inflammasome responses...
Scientists have discovered yet another function for β-secretase (BACE1), the enzyme that kick-starts amyloidogenic processing of the amyloid-β precursor protein...
Mouse studies point to a new pathway that mediates motor neuron disease caused by mutations in superoxide dismutase 1.
Struggles to develop therapeutic antibodies for prion disease teach scientists how prion protein may kill neurons.
No filters selected