Did you know? The NACC’s brain tissue comes with extensive clinical and cognitive data, enabling in-depth studies.
Researchers at a recent Keystone symposium compared the properties of microglia with those of other macrophages in the body. The cells acquire their unique personalities through both their origins and their present environment.
Researchers at Keystone attempted to distinguish microglia from other macrophages in the body, both in form and function, and monitor the way each behaves during disease.
Researchers sequenced the exomes of nearly 3,000 people with ALS to identify the new gene.
Hollywood has discovered the narrative power of neurodegenerative diseases.
Two studies suggest that the anti-inflammatory interleukin-10 prevents efficient plaque clearance and worsens AD-like pathology in mice.
Alzheimer's Research UK has funded institutes at three universities to turn academic ideas into drug candidates.
A debate has sprung up in response to a Cell essay arguing that the baby was thrown out with the bathwater when a γ-secretase inhibitor failed in Phase 3.
Routine cognitive screening could help doctors spot people at risk of dementia. Two new tests could make screening more accessible.
Skin side effect under investigation.
Large consortium releases epigenome profiles of 111 different tissues. They are already yielding insight into the immune system’s role in Alzheimer’s disease.
Whether cleaning up plaques in AD or mopping up debris in the wake of a stroke, microglia get by with a little help from TREM2.
The Journal of Neuroscience retracted a paper that claimed Aβ does not accumulate inside neurons, and temporarily banished its senior authors.
In mice, the presence of mutant human tau disrupts synaptic signaling and slows down neuronal firing.
Simple survey touted as a potential functional outcome in prevention trials.
No filters selected