By paring back calcium signaling, researchers prevented signs of Alzheimer’s in mice carrying a presenilin mutation. Could the strategy work in humans?
MetLife rewards research on secretases, toxic Aβ transmission.
New twist to fluorescence-based microscopy lets scientists see up-close how Aβ aggregates in living cells.
A candidate reference method for measuring Aβ42 in cerebrospinal fluid brings researchers closer to standardization.
Playing nursemaid, TGF-β helps new neurons in the brain survive, develop, and migrate.
In award-winning documentary, son traces his mother’s progression into Alzheimer’s disease.
A close-up of the protein mayhem within the synaptic bouton offers scientists an unprecedented glimpse of the activity inside.
Big-data project takes on Alzheimer's with a biomarker computational challenge.
The ADCS–PACC, a new cognitive composite test to be used in the A4 prevention trial, detects subtle deficits in older adults with brain amyloid.
AFFiRiS AG claims that a placebo formulation, not their active Aβ vaccine, slowed the progression of Alzheimer's disease in a Phase 2 study.
Researchers link frontotemporal dementia pathology to DNA damage.
Supplements of resveratrol, a compound found in red grapes and wine, improved memory, metabolism, and brain connectivity in a group of overweight older adults.
Brain-training websites tout their games’ potential to boost cognition, but strong evidence and firm backing by the scientific community have yet to surface.
While scientists remain on the fence over whether computer games benefit cognition, some are finding new uses for gaming data in clinical trial research.
Does amyotrophic lateral sclerosis start at the interface between mitochondria and the endoplasmic reticulum?
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