This past August, Alzheimer disease researchers met with colleagues from other fields and with foundation and NIH representatives in Bar Harbor, Maine, at the sixth annual workshop on Enabling Technologies for Alzheimer Disease Research.
To what extent is AD an acceleration of normal aging? This decades-old question receded in favor of the view that AD is a separate process from normal aging when studies showed that patterns of neuronal loss are different in aging and AD.
Genomic/proteomic/metabolomics (OMICS) research in AD remains in its infancy. Most studies stall after discovering lists of hundreds of genes whose expression changes in the chosen comparison.
APP Function: A Report from Bar Harbor APP and Axonal Transport: A Report from Bar Harbor BBB/Brain Vasculature: A Report from Bar Harbor Aging and AD: A Report from Bar Harbor Enabling Technologies: A Report from Bar Harbor Recommendations: A Report from ...
In August 2005, a group of researchers from inside and outside the field of Alzheimer disease met in Bar Harbor, Maine, with foundation and NIH representatives for two days of presentations and discussion at the fifth annual workshop on Enabling Technologies for Alzheimer's Disease Research.
It is widely accepted that at least a fraction of APP is actively transported along the axon to the nerve terminal and does not return to the cell body.
After release, some Aβ is degraded locally, a second fraction leaves the brain through interstitial fluid drainage and along brain arterioles, while another fraction is actively transported by proteins, such as LRP and glycoprotein-P, across the blood-brain barrier (BBB) into systemic circulation.
This workshop has an enduring interest in facilitating the import into AD research of new technologies developed in other areas. This year an approach was presented that makes it possible to watch neurons grow and change over time inside living mice.
Clearly, the greatest risk factor for AD is advanced age, but a satisfying explanation of the link between aging and AD remains uncertain. To understand this connection, it is argued that a better understanding of "normal" aging is needed.
Recommendations for future research following the Enabling Technologies for Alzheimer's Disease Workshop in Bar Harbor, ME
Enabling Technologies 2004 Workshop Summary Major Points of Discussion and Ideas for Future Directions Enabling Technologies for Alzheimer Disease Research: 2004 Bar Harbor Workshop ...
This report summarizes discussions and recommendations made at the fourth annual workshop on Enabling Technologies for Alzheimer's disease (AD), held in August 2004 in Bar Harbor, Maine.
Major points of discussion and ideas for future directions from the Enabling Technologies for Alzheimer's Disease 2004 Workshop in Bar Harbor, Maine.
This is a list of final recommendations for future actions from the Enabling Technologies for Alzheimer's Disease Workshop in Bar Harbor, Maine.
Enabling Technologies 2003 Workshop Summary Recommendations: A Report from Bar Harbor 2003 Enabling Technologies for Alzheimer Disease Research: 2003 Bar Harbor Workshop ...
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