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Role of the Motor in Motor Neuron Diseases

In today's Science, researchers report that mutations in the protein dynein—the motor that drives the transport of large molecules from the synaptic terminal back to the neuron’s cell body—can lead to forms of neurodegeneration reminiscent of motor neuron diseases such as amyotrophic lateral sclerosis (ALS)...

Diagnosis of AD—Does Spinal Fluid Hold the Key?

In this week's Journal of the American Medical Association, researchers report a correlation between Alzheimer's disease (AD) and the appearance in the cerebrospinal fluid (CSF) of two proteins thought to play major roles in the progression of the disease—amyloid β42 (Aβ42) and tau...

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