A debate has sprung up in response to a Cell essay arguing that the baby was thrown out with the bathwater when a γ-secretase inhibitor failed in Phase 3.
Alzheimer's Research UK has funded institutes at three universities to turn academic ideas into drug candidates.
Two studies suggest that the anti-inflammatory interleukin-10 prevents efficient plaque clearance and worsens AD-like pathology in mice.
Hollywood has discovered the narrative power of neurodegenerative diseases.
At Keystone, scientists reported that TREM2 may promote the survival of cells surrounding plaques, but where these cells come from and what they do is still up for grabs.
Alzheimer’s Disease Research Summit 2015: Three Years In Alzheimer's Disease Research Summit 2015: Expanding the Horizon The National Institutes of Health hosted a meeting earlier this month as leaders in Alzheimer’s and other diseases met in ...
At an NIH conference in Washington, D.C., experts from beyond Alzheimer’s research discussed ways to beef up data collection and patient participation.
At the first NIH summit since the National Plan to Address Alzheimer’s was implemented back in 2012, scientists discussed progress made and put forth a new set of goals.
Researchers sequenced the exomes of nearly 3,000 people with ALS to identify the new gene.
Researchers at Keystone attempted to distinguish microglia from other macrophages in the body, both in form and function, and monitor the way each behaves during disease.
Researchers at a recent Keystone symposium compared the properties of microglia with those of other macrophages in the body. The cells acquire their unique personalities through both their origins and their present environment.
Did you know? The NACC’s brain tissue comes with extensive clinical and cognitive data, enabling in-depth studies.
Worldwide, brain banks are combining their holdings into large databases in an effort to better support neurodegenerative disease research.
Banked brain tissue enables crucial advances in the understanding and treatment of degenerative disorders. As appreciation of the many different variants of neurodegenerative disease is growing, well-preserved tissue is in more demand than ever. Are the ...
Researchers strongly agree that brain banks are indispensable for important discoveries in neurodegenerative disease, but funding shortfalls now threaten to stall the pace of progress.