Paper Alert: Antisense Oligonucleotide Therapy Safe for ALS?
An oligonucleotide designed to tamp down an enzyme that causes amyotrophic lateral sclerosis seems safe...
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An oligonucleotide designed to tamp down an enzyme that causes amyotrophic lateral sclerosis seems safe...
What if you could diagnose Alzheimer’s disease at an early stage by examining a person’s eyes?...
Using stem cells to replace inhibitory neurons in the hippocampi of adult epileptic mice reduced hyperexcitability, seizures, and behavioral deficits...
People with psychopathic tendencies—who may constitute upwards of 15 percent of prison populations—poorly activate parts of the brain responsible for empathy...
Topline data yesterday showed that intravenous immunoglobulin (IVIG) therapy, known as Gammagard™, failed to meet primary endpoints of slowing cognitive and functional decline...
In the study of ALS, lower motor neurons in the spine have received the lion's share of attention—but now there is a tool to focus on the role of upper motor neurons in the cortex...
Researchers using genomewide screens have identified two new loci for sporadic amyotrophic lateral sclerosis genes in the Han Chinese population...
For decades scientists have sought a way to sneak large drugs across the blood-brain barrier...
Microglia have taken center stage in Alzheimer’s disease (AD) research recently...
Why are women at greater risk for Alzheimer's disease?...
Rather than sequestering Aβ to prevent its clearance from the brain, ApoE may indirectly block the peptide’s path to breakdown...
A new recipe for cooking up cholinergic neurons from stem cells may help researchers study what goes wrong with these cells in Alzheimer’s disease...
When leaky blood vessels damage the brain, the organ’s stem cell niche dispatches a specialist crew of astrocytes to stop the bleeding...
Mutations that cause frontotemporal dementia may also predispose carriers to Alzheimer’s dementia...
As DIAN’s Scope Widens, Funding Narrows Dominantly Inherited Alzheimer Network Pharma Consortium Meeting 2013